What is Gel-One Cross-Linked Hyaluronate?

Gel-One Cross-Linked Hyaluronate is a transparent, sterile, and viscoelastic gel made from sodium hyaluronate (hyaluronan). The hyaluronan used to make Gel-One comes from rooster combs and is highly purified.

Hyaluronan is a natural substance found in high amounts in synovial joints. It acts like a lubricant and shock absorber in the joint and is needed for the joint to work properly.

What is viscosupplementation?

Viscosupplementation is a treatment for osteoarthritis (OA) of the knee in which an injection of sodium hyaluronate is delivered directly into the joint space. Viscosupplementation has been known to relieve pain associated with OA of the knee. There are many different viscosupplements available, Gel-One Cross-Linked Hyaluronate is one option.

Why choose Gel-One Hyaluronate?

Intra-articular (into the joint) viscosupplementation has been available in the U.S. market for a number of years. Gel-One Hyaluronate is the first to offer a convenient single-injection treatment with a low volume of only 3mL.

How is Gel-One administered

 

 


Indications for use
Gel-One Hyaluronate is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, non-steroidal anti-inflammatory drugs (NSAIDs) or simple analgesics, e.g., acetaminophen.

Important safety information
Before using Gel-One Hyaluronate, tell your doctor if you are allergic to hyaluronan products, cinnamon, or products from birds such as feathers, eggs, and poultry. Gel-One Hyaluronate is only for injection into the knee, performed by a doctor or other qualified health care professional. You should not receive Gel-One Hyaluronate injection if you have a skin disease or infection around the area where the injection will be given. Gel-One Hyaluronate has not been tested to show pain relief in joints other than the knee and for conditions other than OA. Gel-One Hyaluronate has not been tested in patients who are pregnant, mothers who are nursing, or anyone under the age of 21. You should tell your doctor if you think you are pregnant or if you are nursing a child. Talk to your doctor before resuming strenuous or pro-longed weight-bearing activities after treatment. The effectiveness of repeat treatment cycles of Gel-One Hyaluronate has not been established. The side effects most commonly seen after injection of Gel-One Hyaluronate in the clinical trial were knee pain, swelling, and/or fluid build-up around the knee. These reactions are generally mild and do not last long. If any of these symptoms or signs appear after you are given Gel-One Hyaluronate or if you have any other problems, you should call your doctor. Ask your surgeon if you are a candidate and discuss potential risks. For additional information, call 1-800-447-5633 , or visit www.zimmerbiomet.com.

This material is intended for U.S. patients.

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The information herein is of a general nature and does not represent or constitute medical advice or recommendations and is for general education purposes only. This information is not meant to replace the specific verbal and written recommendations and instructions provided by your surgeon for your specific situation. Patient treatment plans and outcomes will vary.

Results may vary.  Not all patients are candidates for this product and/or procedure. Only a medical professional can determine the treatment appropriate for your specific condition.  Appropriate post-operative activities and restrictions will differ from patient to patient. Talk to your surgeon about whether joint replacement is right for you and the risks of the procedure, including the risk of implant wear, loosening, or failure.